Section edited by Martin Lercher and Itai Yanai
Systems biology aims to build and apply models for biological systems too complex to be understood intuitively. The systems may comprise, for example, genes, their products, or metabolites, but the focus of the research should be the connections between the parts rather than the parts themselves. Suitable research includes work on systems at all scales, including, but not limited to, metabolic networks, signalling networks, and developmental pathways. Theoretical work should lead to testable predictions that can be applied to biological data. Evolutionary comparisons of systems are particularly welcome, as are analyses of systems-level properties and their relations to biological function.