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The mutation spectra of the TP53 gene and other tumor suppressors contain multiple hotspots, i.e., sites of non-random, frequent mutation in tumors and/or the germline. The origin of the hotspots remains unclear,...
Citation: Biology Direct 2006 1:4
Whether MHC molecules undergo concerted evolution or not has been the subject of a long-standing debate.
Citation: Biology Direct 2006 1:2
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