Fig. 5
From: Loss of AMPK activity induces organelle dysfunction and oxidative stress during oocyte aging
AMPK maintains ER and Golgi apparatus in mouse oocytes. (A) The representative images of ER distribution in the oocytes after AMPK inhibition. Blue, ER. Bar = 20 μm. (B) The relative ER fluorescence intensity in the oocytes after AMPK inhibition. ***p < 0.001. (C) The representative images of Golgi apparatus distribution in the oocytes after AMPK inhibition. Green, Golgi apparatus; blue, DNA. Bar = 20 μm. (D) The relative Golgi apparatus fluorescence intensity in the oocytes after AMPK inhibition. ***p < 0.001. (E) The representative images of lysosome distribution in the oocytes after AMPK inhibition. Red, lysosome; blue, DNA. Bar = 20 μm. (F) The relative lysosome fluorescence intensity in the oocytes after AMPK inhibition. **p < 0.01