Fig. 7From: Unlocking hepatocellular carcinoma aggression: STAMBPL1-mediated TRAF2 deubiquitination activates WNT/PI3K/NF-kb signaling pathwayA In HCCLM3 cells, gradient overexpression of STAMBPL1 resulted in a reduced ubiquitination level of TRAF2. B In Hep3B cells, gradient overexpression of STAMBPL1 resulted in a reduced ubiquitination level of TRAF2. C In HCCLM3 cells, the ubiquitination level of TRAF2 elevated following the downregulation of STAMBPL1. D In Hep3B cells, the ubiquitination level of TRAF2 elevated following the downregulation of STAMBPL1. E IP and WB experiments revealed that STAMBPL1 mediates deubiquitination modification of TRAF2 through K63 ubiquitin sitesBack to article page