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Fig. 4 | Biology Direct

Fig. 4

From: RARRES1 inhibits hepatocellular carcinoma progression and increases its sensitivity to lenvatinib through interaction with SPINK2

Fig. 4

Regulation of RARRES1 expression influenced cell migration and EMT with or without lenvatinib treatment. (A) Representative images and statistical analysis of data from transwell assays in Huh7 and SKHEP1 cells transfected with siCtrl, siRARRES1, siCtrl + lenvatinib, and siRARRES1 + lenvatinib. (B) Representative images and statistical analysis of data from transwell assays in Huh7 and SKHEP1 cells transfected with Ctrl, RARRES1, Ctrl + lenvatinib, and RARRES1 + lenvatinib. (C) Protein expression of EMT markers (E-Cadherin and Vimentin) in Huh7 and SKHEP1 cells transfected with siCtrl, siRARRES1, siCtrl + lenvatinib, and siRARRES1 + lenvatinib, or Ctrl, RARRES1, Ctrl + lenvatinib, and RARRES1 + lenvatinib. **P < 0.01, ***P < 0.001

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