Fig. 10
From: The oncogenic role and regulatory mechanism of PGK1 in human non-small cell lung cancer
Role of MCM4 in PGK1-mediated NSCLC progression. a Cell proliferation was detected via the CCK-8 assay. b Cell colony-forming ability was measured using the colony formation assay. c Cell migration and invasion were examined utilizing the Transwell assay. d The effects of PGK1 mutation on p-ERK and MCM4 levels were detected through Western blotting. e Diagram showing the regulation mechanism of PGK1 in NSCLC progression. MUT, pcDNA3.1( +)-PGK1 wild-type plasmid; MUT, pcDNA3.1( +)- PGK1 mutant plasmid. *P < 0.05,**P < 0.01