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Fig. 2 | Biology Direct

Fig. 2

From: Dysregulation and antimetastatic function of circLRIG1 modulated by miR-214-3p/LRIG1 axis in bladder carcinoma

Fig. 2

Upregulation of circLRIG1 suppresses bladder carcinoma cell proliferation. A qRT-PCR analysis of circLRIG1 mRNA levels in bladder carcinoma cell lines (UMUC3 and T24) transfected with OE-vector or OE-circLRIG1 plasmids. B Cell viability in (A) was determined by CCK-8 assay. C Colony formation assay to determine the colony number of cells in (A). D Flow cytometry analysis to determine apoptosis rate of cells in (A). E Tumor volume was measured at 0, 7, 14, 21, and 28 days. F Tumor weight was measured at 28 days of the xenograft experiment. Experiments were performed in triplicate. “**” indicates P < 0.01

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