Preliminary insights into RNA in CSF of pediatric SMA patients after 6 months of nusinersen

Biology Direct

Table 3 Statistically significant DE cfRNAs in CSF of “heterogeneous” SMA patients at T6 compared to T0, and of “homogeneous” SMA patients at T6 compared to T0

mRNAs, lncRNAs and “other biotype” (processed pseudogenes, unprocessed pseudogene and untranscribed unprocessed pseudogenes) number is represented in terms of up-regulated transcripts, down-regulated transcripts, subtotal and total. Transcripts were considered as DE when |log2(T6/T0)| was ≥ 0.5 and a FDR was ≤ 0.1

ISSN: 1745-6150