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Fig. 7 | Biology Direct

Fig. 7

From: Circular RNA hsa_circ_0067842 facilitates tumor metastasis and immune escape in breast cancer through HuR/CMTM6/PD-L1 axis

Fig. 7

CMTM6 knockdown attenuated the promotion of overexpressing hsa_circ_0067842 on the metastasis and immune escape of BC. A Transwell migration and invasion assays assessing the changes in the migratory and invasive capabilities of MCF-7 in rescue experiments. B Ki-67 staining was used to observe the PBMCs proliferation in rescue experiments. C Flow cytometry was used to determine the percentage of CD8+ T cells in rescue experiments. D LDH cytotoxicity assay was used to detect the cytotoxicity of PBMCs in rescue experiments. E Mechanism of hsa_circ_0067842 in metastasis and immune escape of BC. The experiments were performed three times, and data are represented as mean ± SD, nsP > 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001

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