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Fig. 6 | Biology Direct

Fig. 6

From: PHF5A regulates the expression of the DOCK5 variant to promote HNSCC progression through p38 MAPK activation

Fig. 6

PHF5A inhibition reverses the effect of the DOCK5 variant in HNSCC

(A) CCK-8 assays showed that PHF5A inhibition reversed the pro-proliferative effect of the DOCK5 variant in JHU011 and Tu686 cells. (B) Colony formation assays showed that PHF5A inhibition reversed the pro-colony formation effect of the DOCK5 variant in JHU011 and Tu686 cells. (C) Cell scratch assays showed that PHF5A inhibition reversed the pro-migratory effect of the DOCK5 variant in JHU011 and Tu686 cells. (D) Transwell invasion assays showed that PHF5A inhibition reversed the pro-invasive effect of the DOCK5 variant in JHU011 and Tu686 cells. NC, negative control; si1, PHF5A siRNA1 group; EV, empty vector group; OE, DOCK5 variant overexpression group

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Biology Direct

ISSN: 1745-6150

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