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Fig. 1 | Biology Direct

Fig. 1

From: PHF5A regulates the expression of the DOCK5 variant to promote HNSCC progression through p38 MAPK activation

Fig. 1

PHF5A promotes the expression of the DOCK5 variant in HNSCC

(A) Top 10 upregulated and downregulated spliceosome genes between patients with higher and lower DOCK5 variant expression in TCGA HNSCC data. (B) The expression of PHF5A in groups of patients with high and low DOCK5 variant expression in TCGA HNSCC data. (C) The expression of PHF5A and DOCK5 variants following downregulation of PHF5A in JHU011 and Tu686 cells and upregulation of PHF5A in FaDu cells. ***: P < 0.001, **: P < 0.01, *: P < 0.05, ns: not significant. Ctrl indicates control; EV, empty vector group; OE, PHF5A overexpression group; WT, wild-type

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Biology Direct

ISSN: 1745-6150

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