Fig. 6
From: PSMD3-ILF3 signaling cascade drives lung cancer cell proliferation and migration
PSMD3 drives tumor growth in vivo by ILF3. (A) Tumor size in nude mice among Ctrl, PSMD3, and PSMD3 + YM155 groups was sacrificed at day 42. Images of the xenograft mice with tumors are displayed. (B) The measurement of tumor volumes of nude mice among three groups was made with digital calipers at day 7, 14, 21, 28, 35 and 42. (C) The weight of xenograft tumors was measured among three mice groups at day 42. (D) IHC images of ki67, PSMD3 and ILF3 in three group tumor tissues. Scale bars, 100 μm. (E) The protein expression of PSMD3, ILF3, pEGFR and EGFR in tumor tissues among three groups were detected using western blot. ** p < 0.01