Fig. 2

Differentially expressed genes in IL-4–treated APs. A Transcriptomic analysis of control and IL-4–treated APs (four-day sample). The mRNA-seq results are presented as a volcano plot (Total 18,345 genes). The genes of log2 fold change > 1 (red) or < -1 (blue) with p.adj < 0.05 are highlighted. Pgc1-α, Ear2, and Tmem26 are labeled as the beige adipogenic markers. B KEGG pathway analysis of upregulated (log2 fold change > 1, p.adj < 0.05, upper panel, red) and downregulated (log2 fold change < -1, p.adj < 0.05, lower panel, blue) genes. The number of genes that belongs to each pathway is indicated by circle size and significance (p-value) is presented by color