Fig. 5

LINC01003 knockdown represses glioma growth in vivo. A A subcutaneous xenograft tumor model was generated by transfecting U87MG cells with shNC or shLINC01003. Tumors were removed from the nude mice and photographed at the end of experiment. B Once the mice were injected with the cells, he tumor volume in nude mice was measured every 5 days. The volume curves were plotted from day 5 to day 30. C Quantification of tumor weight in nude mice from (A). D RT-qPCR was used to determine the expression of LINC01003 in the tumors from nude mice. E Western blot was used to detect the expression levels of p-FAK and CAV1 in the tumors from nude mice. Data represent the mean ± SD; *P < 0.05, **P < 0.01, and ***P < 0.001