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Fig. 1 | Biology Direct

Fig. 1

From: TM4SF1 upregulates MYH9 to activate the NOTCH pathway to promote cancer stemness and lenvatinib resistance in HCC

Fig. 1

High levels of TM4SF1 expression are associated with poor prognosis in hepatocellular cancer. A Results of immunohistochemical analysis of HCC tissue microarray showed that the expression of TM4SF1 in HCC tissues increased significantly (n = 90). B Hepatocellular carcinoma tissues were graded according to IHC staining index. C Analysis of the 90 HCC patients revealed that patients with low TM4SF1 expression had a higher overall survival rate than patients with high TM4SF1 expression. D Univariate and multivariate Cox regression analysis of overall survival in 90 HCC patients. E According to the results of qPCR, HCC cells have significant levels of TM4SF1 expression. F Results of the WB analysis showed that TM4SF1 was highly expressed in HCC cells. *P < 0.05; **P < 0.01; ***P < 0.001

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Biology Direct

ISSN: 1745-6150

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