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Fig. 8 | Biology Direct

Fig. 8

From: LncRNA RP11-620J15.3 promotes HCC cell proliferation and metastasis by targeting miR-326/GPI to enhance glycolysis

Fig. 8

RP11-620J15.3 is directly regulated by the transcription factor TBP. A Transcription factors that may regulate the transcription of RP11-620J15.3 were identified by prediction databases (tfTarget, GeneCards, and JASPAR). B, C The expression levels of TBP and RP11-620J15.3 in HCC cells with TBP knockdown were verified by qRT-PCR and WB. D, E Pearson’s correlational analysis of RP11-620J15.3 and TBP in the TCGA-LIHC dataset and 80 pairs of tissues from Zhengzhou University. F The CHIP assay results confirmed the direct binding between TBP and the RP11-620J15.3 promoter region. G The binding sequence of TBP and RP11-620J15.3 was predicted from the JASPAR database. *p < 0.05, **p < 0.01, ***p < 0.001

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