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Fig. 2 | Biology Direct

Fig. 2

From: LncRNA RP11-620J15.3 promotes HCC cell proliferation and metastasis by targeting miR-326/GPI to enhance glycolysis

Fig. 2

RP11-620J15.3 promotes HCC proliferation and metastasis. A Expression of RP11-620J15.3 in Huh-7 and HCC-LM3 cells transfected with shNC and RP11-620J15.3 targeting shRNA. B, C CCK-8 and colony formation assay demonstrated the proliferation ability of Huh-7 and HCC-LM3 cells. D Scratch wound-healing assay revealed the cell-migration ability. E Transwell Matrigel invasion assay demonstrated cell-invasion ability. F A xenograft model was established from control or stable RP11-620J15.3 knockdown HCC-LM3 cells and used to evaluate the weight of the anatomical tumor. G The metastasis in the lungs of nude mice injected with shNC or RP11-620J15.3-sh2 HCC cells. Magnification, 100 × . *p < 0.05, **p < 0.01, ***p < 0.001

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