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Fig. 6 | Biology Direct

Fig. 6

From: circACTR2 attenuates gemcitabine chemoresiatance in pancreatic cancer through PTEN mediated PI3K/AKT signaling pathway

Fig. 6

Targeting circACTR2 in vivo retards PC GEM resistance

A Tumor volume was measured every four days in OE-circ and OE-NC groups after the gemcitabine injections (n = 4). B Pictures of tumors and C tumors weight in OE-circ and OE-NC groups 4 weeks after the GEM treatment. Immunohistochemical staining of PCNA D and tunnel E in OE-circ and OE-NC group tumors (×200). Percentage of PCNA-positive and tunnel-positive cells was shown for each group. *P < 0.05; **P < 0.01

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