Fig. 2
From: Image-based modeling of vascular organization to evaluate anti-angiogenic therapy
Evaluation process and statistical analysis: Results for healthy organs. a Schematic representation of the approach for determine variables used in principal component analysis (PCA). b PCA for the healthy tissues. Orientations of the three highest ranked variables are shown as blue arrows. c Relative perfused vessel volume (rPVV) as fraction of the whole tissue volume. n ≥ 6. d Average vessel segment length in selected organs. n ≥ 6. e Average vessel segment diameter in selected organs. n ≥ 6. f Vessel orientation angle within the XY-plane in selected organs. Angles centered around most frequent orientation at 0°. n ≥ 6, for clarity only the average values are shown. Error bars: ± SEM. Asterisks display results from statistical tests with *: P < 0.05, **: P < 0.01, ***: P < 0.001, ****: P < 0.0001