Skip to main content
Fig. 6 | Biology Direct

Fig. 6

From: Long-term administration of Western diet induced metabolic syndrome in mice and causes cardiac microvascular dysfunction, cardiomyocyte mitochondrial damage, and cardiac remodeling involving caveolae and caveolin-1 expression

Fig. 6

The pathological cardiac remodeling in the Western diet-induced MS mice. A Heart weight/body weight ratio was measured in vivo. B, C Cardiac function was examined by M‐mode echocardiography left ventricular end-systolic diameter (LVESd), inter-ventricular septal thickness in diastole (IVSd), inter-ventricular septal thickness in systole (IVSs), posterior LV wall thickness in diastole (PWTd), and posterior LV wall thickness in systole (PWTs). **P < 0.01, ***P < 0.001. D, E Cross-section cell area was examined and quantified by H&E staining. ***P < 0.0001. F, G Sarcomere length was measure and quantified using TEM analysis. ***P < 0.0001. H–J The BNP, cytochrome c (Cyt c), and cleaved caspase-3 (cleaved casp-3) protein expression in cardiac tissue were examined and quantified by immunohistochemistry and western blot assay. *P < 0.05, **P < 0.01

Back to article page

Biology Direct

ISSN: 1745-6150

Contact us