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Fig. 3 | Biology Direct

Fig. 3

From: Long-term administration of Western diet induced metabolic syndrome in mice and causes cardiac microvascular dysfunction, cardiomyocyte mitochondrial damage, and cardiac remodeling involving caveolae and caveolin-1 expression

Fig. 3

The MS induced cardiac microvascular endothelial dysfunction in vivo. A The cardiac microvascular ultrastructure change was examined by TEM assay. EC, endothelial cell; CM, cardiomyocyte; V, vascular; BM, basement membrane; ECM, extracellular matrix; P, pericyte cells; red arrow, endothelial cell rupture; blue arrow, damaged endothelial cell. B, C The eNOS mRNA and protein expression were examined by real-time PCR and Western blot assay. D The caveolin-1 and eNOS expression and interaction was measured by immunostaining and confocal microscope assay. E Endothelial adhesion molecular VE-cadherin and β-catenin expression and interaction was measured by immunostaining and confocal microscope assay. *P < 0.05; ***P < 0.001; ***P < 0.001

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Biology Direct

ISSN: 1745-6150

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