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Table 4 Correlation between DKK2 expression and clinicopathological features in 96 NSCLC patients

From: Upregulation of long intergenic non-coding RNA LINC00326 inhibits non-small cell lung carcinoma progression by blocking Wnt/β-catenin pathway through modulating the miR-657/dickkopf WNT signaling pathway inhibitor 2 axis

Parameters

Group

N

Expression of DKK2

P value

Low, n (%)

High, n (%)

Age (years)

 ≤ 58

47

25 (53.19)

22 (46.81)

0.3110

 > 58

49

21 (42.86)

28 (57.14)

 

Gender

Female

48

20 (41.67)

28 (58.33)

0.2203

Male

48

26 (54.17)

22 (45.83)

 

Tumor size (cm)

 < 3

45

19 (42.22)

26 (57.78)

0.2941

 ≥ 3

51

27 (52.94)

24 (47.06)

 

TNM stage

I–II

49

18 (36.73)

31 (63.27)

0.0042

III–IV

47

31 (65.96)

16 (34.04)

 

Smoking history

Yes

53

22 (41.51)

31 (58.49)

0.0.2422

No

43

23 (53.49)

20 (46.51)

 

Lymph node metastasis

Yes

50

33 (66.00)

17 (34.00)

0.0011

No

46

15 (32.61)

31 (67.39)

 

Differentiation

Well/moderate

49

12 (24.49)

37 (75.51)

0.0039

Poor

47

25 (53.19)

22 (46.81)

 
  1. NSCLC non-small cell lung cancer