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Fig. 4 | Biology Direct

Fig. 4

From: M2 macrophage-derived exosomal miR-193b-3p promotes progression and glutamine uptake of pancreatic cancer by targeting TRIM62

Fig. 4

TRIM62 is a target of miR-193b-3p. A Sequences of miR-193b-3p and miR-193b-3p-binding site. B Effects of miR-193b-3p mimics/inhibitors on the luciferase activity of TRIM62 3ʹUTR wild-type and mutant. Effect of C, D miR-193b-3p mimics/inhibitors or D, E M2/Inhibitor-exo or M2/NC-exo transfection on TRIM62 expression in SW1990 cells. Data are expressed as mean ± SD (n = 3). *P < 0.05, **P < 0.01, ***P < 0.001 versus NC or M0-exo. ###P < 0.001 versus M2/NC-exo.

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