Fig. 4
From: In silico optimization of RNA–protein interactions for CRISPR-Cas13-based antimicrobials
In silico docking evaluation of the Cas13a proteins of the best experimental metrics. The iRMSD from the in silico docking experiments of the crRNAs with the Cas13a protein using HDOCK. The 10 best models were retained from HDOCK and the experiments were performed template-free or template-based. Each box represents the results of 60 docking experiments. The 3-D structure below each box shows the GT structure (magenta), the computer selected best model (blue), and the human selected best model (green) docked on the corresponding Cas13a protein (grey). Except for 5W1H, the computer selected best model coincided with the human selected best model (green)