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Fig. 5 | Biology Direct

Fig. 5

From: Downregulation of amphiregulin improves cardiac hypertrophy via attenuating oxidative stress and apoptosis

Fig. 5

Effects of AREG on oxidative stress. a, The increase of Ang II induced 8-OHdG positive cells in mice heart was alleviated by AREG downregulation. Magnification 400X. b, The enhancements of Ang II induced superoxide anions, Nox activity and MDA in mice heart were alleviated by AREG downregulation. c, The enhancements of Ang II induced superoxide anions, Nox activity and MDA in the NRCMs were alleviated by AREG downregulation. d, The enhancements of Ang II induced superoxide anions, Nox activity and MDA in the HL-1 cells were alleviated by AREG downregulation. n = 8 (a and b) or 10 (c and d) for each group. Express the results as mean ± SEM. Magnification

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Biology Direct

ISSN: 1745-6150

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