Fig. 1

p53 rewires pancreatic cancer lipidome. a, b Heatmap and Volcano plot showing global changes of lipids upon depletion of p53. For Volcano plot a p value < 0.05 and a − 1.5 > fold change > 1.5 were used as threshold. Lipid abundancies are sown as signal intensities (AU: arbitrary units). N = 5 biological replicates per condition. c, d Violin plots showing the significantly modulated lipid classes after p53 knockdown. p values are indicated. e Violin plots showing the significantly modulated lipid classes in the conditioned medium after p53 knockdown. p values are indicated