Skip to main content
Fig. 4 | Biology Direct

Fig. 4

From: Circ_0067680 expedites the osteogenic differentiation of human bone marrow-derived mesenchymal stem cells through miR-4429/CTNNB1/Wnt/β-catenin pathway

Fig. 4

Circ_0067680 participates in the activation of Wnt/β-catenin signaling pathway. A The activity of common signaling pathways when circ_0067680 was depleted was detected by luciferase reporter assay. B Protein levels of β-catenin, p65, p-p65, AKT and p-AKT were analyzed under the condition of circ_0067680 inhibition. C The expression of nuclear β-catenin, c-myc, cyclin D1 at protein level was detected when circ_0067680 was inhibited. D TOP/FOP flash assay assessed the activity of Wnt/β-catenin signaling pathway after circ_0067680 was silenced. *P < 0.05, **P < 0.01

Back to article page

Biology Direct

ISSN: 1745-6150

Contact us