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Fig. 3 | Biology Direct

Fig. 3

From: Conserved sequence motifs in human TMTC1, TMTC2, TMTC3, and TMTC4, new O-mannosyltransferases from the GT-C/PMT clan, are rationalized as ligand binding sites

Fig. 3

Structure models of TMTC1/2/3/4 with ligands. The cartoon representation of model TMTC1/2/3/4 (from top to bottom) with docked DPM is shown in side- (left column) and top-view (middle column). Close-up (right column) of the binding pocket of TMTCs with docked DPM (cyan color sticks) and with important residues (HKSY residues of the conserved SHKSYRP motif M2 in EL1; K and E from motif M4 in EL3) presented in yellow color sticks; the divalent metal ion (modelled as zinc) is shown in gray color

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Biology Direct

ISSN: 1745-6150

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