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Fig. 9 | Biology Direct

Fig. 9

From: Reconstruction of endosomal organization and function by a combination of ODE and agent-based modeling strategies

Fig. 9

Lipid and Rab dynamics in individual endosomes. Repast stored the time series of all the network of reactions (including lipid metabolism, HexA release, and Rab dynamics) calculated in COPASI for each endosome (Additional file 3). Four endosomes were selected with different initial pH. a-d Changes in HexA and lipid content of each endosome calculated by COPASI using the initial values sent by Repast. The concentrations were expressed as a percentage of the initial value. e-h. Changes in the Rab content calculated by COPASI using the initial values sent by Repast. The values are expressed as a percentage of the total area of the endosome. Data coming from 4 individual endosomes

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