Fig. 2From: Modeling protein folding in vivoThe protein folding energy landscape of a small protein that is thermodynamically stable in its native conformation. The fast folding pathway in vivo starts from an unstable high-energy state at the top of the mountain. The entropy of the nascent peptide is reduced and the backbone conformational strain is introduced by the motions of the ribosome/chaperone complex in the process that is described in [67, 68] and in the text. Yellow arrow shows fast folding pathway in vivoBack to article page