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Fig. 6 | Biology Direct

Fig. 6

From: The role of cell location and spatial gradients in the evolutionary dynamics of colon and intestinal crypts

Fig. 6

Probability of 2-hit mutant existence at each location, \(P_{2hit}^{exist}(x,T)\). Circles and squares are respectively results of the simulations for asymmetric and symmetric divisions. Dashed lines are analytical results for symmetric divisions, and dotted lines are analytical results for asymmetric divisions (see equation (22) in Additional file 1). Note that dashed lines and dotted lines almost coincide for each division probability function. Parameters are T=10000, u 1=0.001, u 2=0.02, n=20

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