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Table 3 The occurrence of SiMPRes in known structural/functional protein sites/regions. Color codes represent over- and under-representation compared to random. Shades of red show increasing over-representation. The amount of over- and under-representation is given in standard deviation units calculated from 1000 randomly assigned regions. ‘Regions of interest’ marks experimentally characterized protein regions that can be of interest concerning protein function (such as interaction sites, different regions of multifunctional enzymes or regions crucial for biological processes/sub-cellular localizations)

From: Systematic analysis of somatic mutations driving cancer: uncovering functional protein regions in disease development