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Table 2 Twenty-seven main cancer types. Cancer types are shown with the corresponding tissue/organ of occurrence and number of local somatic mutations and originating samples in COSMIC

From: Systematic analysis of somatic mutations driving cancer: uncovering functional protein regions in disease development

Tissue/organ Cancer types Number of local somatic mutations in COSMIC Number of samples Average number of mutations per sample
Bladder Bladder cancer 6 265 3 027 2.07
Blood Acute myeloid leukemia 11 650 5 857 1.99
Chronic myeloid leukemia 1 603 1 041 1.54
Lymphoma 24 572 6 944 3.54
Bone Bone cancer 2 814 706 3.99
Brain Glioblastoma 9 361 2 909 3.22
Neuroblastoma 4 932 619 7.97
Glioma 12 793 2 947 4.34
Medulloblastoma 4 701 728 6.46
Breast Breast cancer 31 544 4 404 7.16
Cervix Cervical cancer 136 132 1.03
Colorectal Colorectal cancer 37 727 25 806 1.46
Esophagus Esophageal cancer 3 659 433 8.45
Head and neck Thyroid cancer 19 975 13 908 1.44
Head and neck carcinoma 75 67 1.12
Kidney Renal cell carcinoma 27 897 1 750 15.94
Liver Hepatocellular carcinoma 19 100 2 091 9.13
Lung Small cell lung cancer 976 208 4.69
Non-small cell lung cancer 19 991 11 236 1.78
Ovary Ovarian cancer 19 286 2 936 6.57
Pancreas Pancreatic cancer 33 776 5 609 6.02
Prostate Prostate cancer 18 813 967 19.46
Skin Melanoma 12 374 7 923 1.56
Squamous cell carcinoma 15 726 3 459 4.55
Basal cell carcinoma 292 251 1.16
Stomach Stomach cancer 7 795 1 430 5.45
Uterus Endometrial cancer 5 722 1 627 3.52
Total 353 555 109 015 3.24