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Fig. 7 | Biology Direct

Fig. 7

From: The cyclin D1 carboxyl regulatory domain controls the division and differentiation of hematopoietic cells

Fig. 7

The progeny of WT and Vav1-Cre +/− Ccnd1 4-5 flox +/+ LSKs in BM reconstituted chimeras. Lethally irradiated (1,700 rad) CD45.1+ CD45.2+ Rag2 mice were injected i.v. with equal numbers (2,500) of LSKs from CD45.1+ WT and CD45.2+ Ccnd1 4-5 flox +/+ mice, expressing the Cre recombinase under the Vav1 promoter (Vav cells), and studied two weeks after BM transfer. Upper graphs show WT and lower graphs Vav cells (a). B220+ BM cells (b). TN thymocytes. Results are from two independent experiments

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