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Table 4 Parameter values that have been specified by locally fitting the vascular tumour growth model to experimental data extracted from [60]

From: Numerical simulation of vascular tumour growth under antiangiogenic treatment: addressing the paradigm of single-agent bevacizumab therapy with the use of experimental data

Study Experimental group λ 1 c d β p K 0 RMSE FOO
  day−1 mg/day · mm3p · kg day−1 · mm−2 mm3p - mm3 mm3  
Dataset 1 Control 4.7129 0.1519 0.0015 - - 159.4476 10.7552 3.31 · 10−2
Treatment 0.6701 0.0991 0.0015 1 4.0606 76.0920 7.0026 1.5 · 10−3
(5 mg/kg)
Dataset 2 Control 0.1340 1.1503 0.0088 - - 650 13.3087 1.12 · 10−2
Treatment 0.1049 0.5236 0.0088 1.4456 3.8916 358.2054 11.7711 6.72 · 10−5
(5 mg/kg)
  1. First-order optimality (FOO) is a measure of the closeness of the solution to the optimum