Table 1 Main annotated functions of the gene families for which environmental homologs were identified

maltose ABC transporter, periplasmic maltose-binding protein

HMQ(127); JM(6)

rhomboid family protein

HMQ(907); AA(95); HA(33); JM(29); BB(18); WL(6)

phage shock protein A, PspA

HMQ(111); JM(10); BB(3); AA(3)

segregation and condensation protein B

HMQ(1083); HA(120); AA(117); JM(39); BB(30); WL(11)

V-type ATP synthase subunit I

HMQ(326); AA(16); JM(15)

protein of unknown function DUF192

HMQ(94); AA(33); HA(23); BB(19); WL(10)

nucleotide kinase

HMQ(9); HA(3)

30S ribosomal protein S8e

HMQ(7); AA(5)

homoserine kinase

HMQ(274); AA(77); HA(43); JM(17); BB(8)

DNA-directed RNA polymerase subunit L

HMQ(4); HA(3)

30S ribosomal protein S24e

HMQ(6)

ribosomal biogenesis GTPase

HMQ(980); JM(32); HA(23); AA(5); WL(4); BB(3)

DNA-directed RNA polymerase I, II, and III, 7.3 kDa polypeptide

HMQ(291); AA(34); WL(5); JM(5)

protein of unknown function DUF167

HMQ(94); AA(62); WL(18); JM(3)

CoA-substrate-specific enzyme activase

HMQ(919); JM(64); AA(9); WL(4)

RNA-binding protein

HMQ(717); JM(52); WL(12); HA(10); BB(8); AA(8)

hypothetical protein

HA(43); AA(29); BB(16) HMQ(9)

protein of unknown function DUF420

AA(18); BB(8); WL(3)

twin arginine-targeting protein translocase

HMQ(344); HA(105); AA(105); BB(31); WL(20); JM(17); MB(8); SI(5); G(3)

protein of unknown function DUF502

HA(87); AA(59) HMQ(47); BB(24); WL(15)

ribonuclease III

HMQ(1370); AA(549); HA(115); JM(66); BB(51); WL(6)

polyprenyltransferase

HMQ(44); AA(44); HA(32); BB(8); WL(7)

Rossmann fold nucleotide-binding protein

HMQ(1133); AA(203); HA(79); JM(46); BB(28); WL(18)

glutamyl-tRNA reductase

HMQ(299); HA(31); AA(31); BB(14); WL(7); JM(7)

50S ribosomal protein L30P

AA(13) HMQ(12); HA(3)

50S ribosomal protein L34e

HMQ(1); HA(1); AA(2)

50S ribosomal protein L14e

AA(7)

Pre-mRNA processing ribonucleoprotein, binding region

HMQ(6)

like-Sm ribonucleoprotein, core

AA(23) HMQ(7); HA(4); BB(3)

30S ribosomal protein S26e

HA(2)

30S ribosomal protein S3Ae

HMQ(5)

30S ribosomal protein S27e

AA(8) HMQ(4)

cobalamin 5'-phosphate synthase

HMQ(871); JM(30); AA(17); HA(15); WL(8); BB(3)

phenylalanyl-tRNA synthetase subunit alpha

HMQ(1698); AA(207); HA(127); JM(66); BB(48); WL(7)

cell division protein and ATP-dependent metalloprotease FtsH

HMQ(1707); HA(338); AA(335); JM(109); BB(79); WL(6)

50S ribosomal protein L1P

HMQ(1231); AA(215); HA(146); JM(65); BB(43); WL(16)

AAA family ATPase, Cell Division Cycle CDC48 subfamily protein

HMQ(10)

methionyl-tRNA synthetase

HMQ(1390); AA(211); HA(103); JM(81); BB(35); WL(7); MB(5)

50S ribosomal protein L2P

HMQ(815); AA(227); HA(147); JM(75); BB(63); WL(3)

50S ribosomal protein L22P

HMQ(1765); AA(256); HA(150); JM(88); BB(53); WL(19); MB(3); SI(3)

inositol monophosphatase

HMQ(1349); HA(342); AA(307); BB(113); JM(55); WL(15)

chaperonin GroEL

HMQ(678); AA(191); HA(128); BB(67); JM(48); WL(5)

50S ribosomal protein L13

HMQ(1827); AA(286); HA(142); BB(63); JM(53); WL(8); MB(4); SI(4)

50S ribosomal protein L5P

HMQ(2379); AA(520); HA(373); JM(150); BB(116); WL(25); MB(9)

30S ribosomal protein S12

HMQ(956); AA(239); HA(155); JM(61); BB(57); SI(20); WL(14); MB(5); G(3)

Bcr/CflA subfamily drug resistance transporter

HMQ(399); JM(19); WL(3)

DNA repair and recombination protein RadA

HMQ(3327); AA(372); HA(195); JM(109); BB(86); WL(21)

50S ribosomal protein L6

HMQ(1402); AA(239); HA(142); JM(73); BB(55); WL(16)

methionine aminopeptidase

HMQ(6396); AA(538); HA(316); JM(217); BB(184); WL(22); LM(3)

ribonuclease HII

HMQ(2476); AA(173); HA(130); JM(60); BB(43); WL(13)

50S ribosomal protein L23

HMQ(2229); AA(253); HA(158); JM(99); BB(46); WL(22); MB(14)

molybdenum cofactor biosynthesis protein A

HMQ(2024); AA(146); JM(62); HA(49); BB(40); WL(17)

50S ribosomal protein L3P

HMQ(1404); AA(205); HA(103); BB(61); JM(61); WL(8); SI(3)

50S ribosomal protein L18e

HMQ(10); AA(5); BB(3); HA(3)

tryptophanyl-tRNA synthetase

HMQ(1877); AA(213); HA(151); JM(52); BB(45); WL(9)

aspartyl-tRNA synthetase

HMQ(3159); AA(348); HA(225); JM(149); BB(95); WL(13)

nicotinate nucleotide adenylyltransferase

HMQ(2308); AA(170); HA(138); JM(73); BB(62); WL(15)

30S ribosomal protein S17P

HMQ(1771); AA(264); HA(137); JM(79); BB(50); WL(23); MB(11); SI(10)

putative RNA methylase

HMQ(1410); HA(35); JM(34); AA(20); BB(6); WL(6)

translation-associated GTPase

HMQ(2629); AA(316); HA(247); JM(97); BB(65); WL(11)

50S ribosomal protein L29

HMQ(1969); AA(219); JM(82); HA(48); BB(24); SI(22); MB(16); WL(12)

appr-1-p processing domain-containing protein

HMQ(805); JM(55); AA(20); WL(5); BB(3)

30S ribosomal protein S7

HMQ(1095); AA(313); HA(165); BB(67); JM(67); SI(10); WL(6); G(3)

TatD-related deoxyribonuclease

HMQ(3338); AA(182); HA(128); JM(86); BB(46); WL(10) ; OM(5)

mevalonate kinase

HMQ(1131); JM(45); AA(16); HA(6)

O-sialoglycoprotein endopeptidase

HMQ(2408); AA(213); HA(163); JM(99); BB(53); WL(5); LM(3)

MiaB-like tRNA modifying enzyme

HMQ(5237); AA(252); HA(197); JM(135); BB(88); WL(12)

50S ribosomal protein L15P

HMQ(1798); AA(174); HA(133); JM(103); BB(56); WL(19); MB(4)

6,7-dimethyl-8-ribityllumazine synthase

HMQ(1365); AA(180); HA(149); JM(50); BB(38); WL(25)

30S ribosomal protein S5P

HMQ(3691); AA(416); HA(299); JM(154); BB(105); WL(23); MB(5)

carbohydrate kinase, YjeF related protein

HMQ(1547); JM(38); HA(27); AA(13); WL(8); BB(6)

ribose-phosphate pyrophosphokinase

HMQ(1807); AA(191); HA(158); JM(70); BB(39); WL(11)

replication factor C small subunit

HMQ(6239); AA(712); HA(225); JM(167); BB(86); WL(19); MB(5)

hydrolase

HMQ(6012); JM(207); HA(45); AA(22); BB(10)

tyrosyl-tRNA synthetase

HMQ(1123); AA(192); HA(128); JM(65); BB(55); WL(6)

50S ribosomal protein L18P

HMQ(14)

Fmu (Sun) domain-containing protein

HMQ(2680); JM(76); AA(50); HA(47); BB(20); WL(12)

30S ribosomal protein S2

HMQ(834); AA(225); HA(130); JM(48); BB(44); WL(8)

leucyl-(isoleucyl-) and (valyl-)tRNA synthetase

HMQ(2653); AA(112); JM(78); HA(75); BB(51); WL(7)