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Table 3 Topology prediction results on the structure benchmark set

From: The human transmembrane proteome

  HMMTOPa Membrain MEMSAT-SVM Octopus Philius Phobius Pro Prodiv Scampi-Msa TMHMM TOPCONS CCTOPa
Sens/res 0.97 0.99 0.96 0.97 0.96 0.97 0.9 0.97 0.99 0.94 0.97 0.99
Spec/res 0.97 0.94 0.99 0.98 0.98 0.97 0.98 0.97 0.98 0.99 0.98 0.99
MCC/res 0.97 0.96 0.97 0.97 0.97 0.97 0.94 0.97 0.98 0.96 0.96 0.99
Acc Tpg /prot 84 76 80 83 81 79 66 82 89 76 78 93
Acc Top /prot 81 0 68 82 74 77 51 67 88 70 76 92
  1. Prediction accuracies of the various topology prediction methods on the structure benchmark set. Sens/res, Spec/res, and MCC/res mean per-residue sensitivity, specificity, and Matthew correlation coefficient, respectively. AccTpg/prot and AccTop/prot mean per/-protein topography and topology accuracies multiplied 100, respectively (apredictions were made without topological constraints)