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Table 6 List of residues from different regions of AspRS strongly binding with tRNAAsp

From: Structure based approach for understanding organism specific recognition of protein-RNA complexes

E. coli

T. thermophilus

S. cerevisiae

Region

R26

R27

N117

Anti-codon binding

R28

R29

R119

L30

L31

Q121

L33

L34

L125

G31

-

-

F35

F36

F127

N84

N82

I179

S32

G33

T124

D86

R84

K180

E93

E91

E188

Q46

Q47

Q138

-

-

L223

R64

R64

N161

R78

R78

V175

-

-

P224

V107

-

V226

T117

-

N227

Hinge region

-

-

L228

-

R115

-

A120

L126

T230

R217

-

R325

Catalytic domain

R222

A229

T331

D224

-

R333

R225

R231

H334

F229

F235

F338

I343

R343

-

Insertion domain

-

-

T424

Catalytic domain

-

-

K428

T558

K552

-

R537

R531

R531

R549

R543

R544

A560

G554

K553

T557

N551

D551

A561

K555

R554

  1. Bold face indicates the set of residues strongly interacting with tRNAAsp. The equivalent residues from other sources, which are not interacting with tRNAAsp are italics"-" indicates gap or no equivalent residues.