Figure 5From: The mechanistic and evolutionary aspects of the 2′- and 3′-OH paradigm in biosynthetic machineryComparison of the second step of the reaction catalyzed by PheRS (red) and AspRS (white). In contrast to other class II aaRSs, in PheRS, the 2′-OH ribose is most suitable for attack on the phenyl-adenylate carboxyl group.Back to article page