Organiztion of the BSL RDHV genome. (A) Schematic representations of tombusvirus, BSL RDHV and porcine circovirus (PCV) genomes: Tombusviruses are linear ssRNA viruses, BSL RDHV and PCV are circular ssDNA viruses. Bars below ORFs indicate protein families detected by InterProScan. (B) Comparison of PCV-1 and BSL RDHV stem-loops: Both BSL RDHV and circoviruses have a conserved stem-loop in the intergenic region upstream of Rep. Black text indicates sequence identity. Nonanucleotide replication origins in the 13nt loop are boxed. Brackets indicate the 9 nucleotide stem preceding hexamer repeats H1 and H2 (gray boxes).