Unrooted phylogram from Bayesian analysis of 279 V-H+PPase sequences from the three superkingdoms of life. Terminal branches of V-H+PPases are labeled with a solid square when the Pfam domain was found duplicated in the sequence. If the domain were found single, the terminal branch has no square. All the branches are labeled with the name of the species and accession number. Eukaryote species are represented with black letters, Bacteria with blue and Archaea with red.