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Table 4 Functional roles of the amino acid sites under adaptive evolution

From: Molecular evolution of rbcL in three gymnosperm families: identifying adaptive and coevolutionary patterns

  Location   
Site Domain Interface Functional roles References
A11V loop 1   To contribute to the holoenzyme thermal stability, catalytic efficiency, and CO2/O2 specificity Kellogg and Juliano (1997) [3]
Q14K     Ott et al. (2000) [106]
K30Q loop 2 LSU dimers   Du and Spreitzer (2000) [107]
I133L βE    Spreitzer and Salvucci (2002) [36]
S143A αD    Spreitzer et al. (2005) [64]
L225I α2 LSUs and SSUs   Makowski et al. (2008) [33]
T262V β4    
G86D βC Rubisco and its activase To affect the contacts between the Rubisco and its activase Du et al. (2003) [108]
S95N βD    Portis (2003) [40]
V99A     Portis et al. (2008) [42]
  1. All positively selected amino acid sites in Table 3 are included.