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Table 4 Functional roles of the amino acid sites under adaptive evolution

From: Molecular evolution of rbcL in three gymnosperm families: identifying adaptive and coevolutionary patterns

 

Location

  

Site

Domain

Interface

Functional roles

References

A11V

loop 1

 

To contribute to the holoenzyme thermal stability, catalytic efficiency, and CO2/O2 specificity

Kellogg and Juliano (1997) [3]

Q14K

   

Ott et al. (2000) [106]

K30Q

loop 2

LSU dimers

 

Du and Spreitzer (2000) [107]

I133L

βE

  

Spreitzer and Salvucci (2002) [36]

S143A

αD

  

Spreitzer et al. (2005) [64]

L225I

α2

LSUs and SSUs

 

Makowski et al. (2008) [33]

T262V

β4

   

G86D

βC

Rubisco and its activase

To affect the contacts between the Rubisco and its activase

Du et al. (2003) [108]

S95N

βD

  

Portis (2003) [40]

V99A

   

Portis et al. (2008) [42]

  1. All positively selected amino acid sites in Table 3 are included.