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Table 2 MicroRNAs associated (P < 0.05) with different genetic subtypes depicting chromosomal location.

From: MicroRNA expression in multiple myeloma is associated with genetic subtype, isotype and survival

Cytogenetic group microRNA Fold change P -value Chromosome
IgH trans (n = 14) miR-590 3.28 1.62E-02 7q11.23
  miR-886 1.63 1.46E-02 5q31.1
  miR-33b 1.48 2.46E-02 17p11.2
  miR-184 -1.43 3.87E-02 15q25.1
  miR-139 -1.44 1.47E-02 11q13.4
  miR-508 -1.63 4.55E-03 Xq27.3
  miR-579 -1.66 2.43E-02 5p13.3
t(11;14) (n = 8) miR-202* 2.16 3.10E-03 10q26.3
  miR-520c 2.05 1.26E-03 19q13.42
  miR-890 2.04 4.39E-02 Xq27.3
  miR-582 1.91 4.06E-02 5q12.1
  miR-122a 1.88 1.40E-02 3p21.31
  miR-526b* 1.86 1.09E-04 19q13.42
  miR-375 -1.74 2.04E-02 2q35
  miR-543 -1.59 3.46E-02 14q33.21
  miR-650 -1.58 4.00E-02 22q11.22
  miR-193a -1.51 1.35E-02 17q11.2
  miR-147b -1.46 2.76E-02 15q21.1
  miR-526a -1.51 4.68E-02 19q13.42
  miR-542 -1.56 1.81E-02 Xq26.3
  miR-301 -2.22 4.80E-02 17q22
  miR-26b -2.62 3.81E-02 2q35
  miR-376a -2.63 2.68E-02 14q33.21
  miR-21 -2.82 5.19E-03 17q23.1
t(4;14) (n = 3) miR-376a 3.48 1.23E-02 14q33.21
  miR-574 3.11 1.23E-02 4p14
  miR-99a 2.53 1.23E-02 21q21.1
  miR-214 2.12 2.77E-02 1q24.3
  miR-577 1.97 3.85E-02 4q26
  miR-342 1.79 3.50E-02 14q32.2
  miR-935 -2.07 3.55E-02 19q13.42
  miR-520c -2.23 3.85E-02 19q13.42
13q(del) (n = 6) miR-221 -9.71 1.18E-04 Xp11.3
  miR-222 -9.50 1.78E-03 Xp11.3
  let-7b -5.15 3.38E-03 22q13.31
  let-7a -4.92 3.72E-03 9q22.32/11q24.1
  let-7c -4.86 6.70E-03 21q21.1
  miR-15a -4.42 6.39E-03 13q14
  miR-20a -4.41 1.47E-03 13q31
  miR-107 -4.40 3.23E-03 10q23.31
  miR-26a -4.37 3.26E-03 3p22.2/12q14.1
  miR-103 -4.30 8.98E-03 5q34/20p13
  miR-142 -4.13 1.15E-03 17q22
  miR-195 -3.97 6.98E-03 17p13.1
  miR-146a -3.92 1.46E-03 5q33.3
  miR-23a -3.80 6.44E-03 19p13.12
  miR-92a -3.77 3.57E-03 13q31
  miR-27a -3.58 2.25E-03 19p13.12
  miR-361 -3.46 4.19E-03 Xq21.2
  miR-145 -3.43 7.10E-03 5q32
  miR-92b -3.37 9.82E-03 13q31
  miR-19a -3.36 5.57E-03 13q31
  miR-199a* -2.93 5.93E-03 19p13.2/1q24.3
  miR-34a -2.89 2.56E-03 1p36.22
  miR-188 -2.79 8.43E-03 Xp11.23
  miR-196a -2.40 5.60E-03 17q21.32
  miR-485 -2.33 4.18E-03 19q13.42
  miR-16 -2.23 7.79E-03 13q14
  miR-493 -1.89 2.46E-03 14q32.2
  1. Comparison between MM cases with (positive fold change) and without (negative fold change) chromosomal abnormality as indicated in text. MicroRNAs also identified by Gutiérrez et al [19] or Lionetti et al [20] are depicted in bold type.