Figure 5

Structural superimposition of the conserved helix-turn-helix (HTH) domains. The structural superimposition was performed using the CE method [72]. Alpha helical structural elements are highlighted by grey shading according to DSSP [73]. The PDB IDs are: 2jvl, C-terminal domain of MBF1 (Trichoderma reesei); PBD ID: 1x57, EDF-1 (human Multiprotein bridging factor 1 α); PDB ID: 1pra, DNA-biding domain (residues 1 to 69) of the bacteriophage 434 repressor; PDB ID: 1y9q, HTH_3 family transcriptional regulator (Vibrio cholerae); PDB ID: 1utx, CYLR2, Transcriptional repressor of cytolysin operon (Enterococcus faecalis); PDB ID: 2b5a, C.BCLI, control element of the BCLI restriction modification system (Bacillus caldolyticus).