The origin of a derived superkingdom: how a gram-positive bacterium crossed the desert to become an archaeon

Biology Direct

Table 1 Essentiality of ribosomal proteins.

Species	Essential ribosomal proteins	P (ribosome is essential)	Essential but absent in Archaea	P-value
Pseudomonas aeruginosa UCBPP-PA14	32	0.5818	8	0.3373
Escherichia coli MG1655	45	0.8182	10	0.055
Bacillus subtilis 168	51	0.9273	14	0.3263
Mycoplasma pulmonis UAB CTIP	47	0.8545	10	0.0204
Francisella novicida U112	49	0.8909	13	0.2505
Helicobacter pylori 26695	29	0.5273	10	0.8493
Mycoplasma genitalium G37	51	0.9273	14	0.3263
Acinetobacter baylyi ADP1	48	0.8727	11	0.0435
Mycobacterium tuberculosis H37Rv	34	0.6182	4	0.0031
Staphylococcus aureus N315	51	0.9273	14	0.3263
Haemophilus influenzae Rd KW20	39	0.7091	9	0.1546

The essentiality of proteins that would need to be lost in the transition from an extant bacterial ribosome to an archaeal one varies from species to species. M. tuberculosis appears preadapted for the losses that would be necessary in the transition to an archaeon.

ISSN: 1745-6150