From: Mitochondrial pathogenic mutations are population-specific
SNP Categories | African (401 genomes) | Non-African (4057 genomes) | U-test p-value |
---|---|---|---|
Synonymous | 21.5 ± 0.5 | 9.7 ± 0.1 | 2.2 × 10-6 |
- Four fold | 12.2 ± 0.3 | 5.0 ± 0.06 | 2.2 × 10-6 |
Nonsynonymous | 7.3 ± 0.2 | 3.9 ± 0.04 | 2.2 × 10-6 |
- Benign | 6.8 ± 0.2 | 3.6 ± 0.03 | 2.2 × 10-6 |
- Damaging | 0.53 ± 0.04 | 0.25 ± 0.009 | 2.2 × 10-6 |
Pathogenic total | 0.21 ± 0.02 | 0.31 ± 0.008 | 1.3 × 10-6 |
- Coding Regions | 0.14 ± 0.02 | 0.24 ± 0.007 | 1.6 × 10-3 |