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Table 4 Average number of minor alleles per genome.

From: Mitochondrial pathogenic mutations are population-specific

SNP Categories

African (401 genomes)

Non-African (4057 genomes)

U-test p-value

Synonymous

21.5 ± 0.5

9.7 ± 0.1

2.2 × 10-6

- Four fold

12.2 ± 0.3

5.0 ± 0.06

2.2 × 10-6

Nonsynonymous

7.3 ± 0.2

3.9 ± 0.04

2.2 × 10-6

- Benign

6.8 ± 0.2

3.6 ± 0.03

2.2 × 10-6

- Damaging

0.53 ± 0.04

0.25 ± 0.009

2.2 × 10-6

Pathogenic total

0.21 ± 0.02

0.31 ± 0.008

1.3 × 10-6

- Coding Regions

0.14 ± 0.02

0.24 ± 0.007

1.6 × 10-3