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Table 1 NR- RTK interactions and their combined scores

From: Application of computational approaches to study signalling networks of nuclear and Tyrosine kinase receptors

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Combined score**

ALK

RARA

0.659

CSF1R

NR3C1

0.700

CSF1R

THRA

0.675

DHTR*

ERBB2

0.786

DHTR

EGFR

0.970

DHTR

ERBB3

0.478

EGFR

RARB

0.461

EGFR

THRA

0.820

EGFR

ESR1

0.971

EPHB4

NR3C1

0.467

EPHB6

ESR1

0.636

ERBB2

RARA

0.637

ERBB2

ESR1

0.971

ERBB2

THRA

0.810

ERBB2

NR1D1

0.441

ERBB3

ESR1

0.700

ERBB3

ESRRB

0.433

ERBB4

ESR1

0.550

ERBB4

PGR

0.588

ESR2

ERBB4

0.631

ESR2

ERBB2

0.777

ESR2

IGF1R

0.594

ESR2

ERBB3

0.689

ESR2

CSF1R

0.747

ESR2

MET

0.561

ESR2

EGFR

0.775

FGFR4

NR1H4

0.509

HNF4A

INSR

0.797

IGF1R

ESR1

0.920

NR2F2

PDGFRA

0.445

NR4A2

EPHB1

0.832

NTRK2

THRA

0.826

PDGFRB

NR3C1

0.545

PGR

EGFR

0.726

PGR

ERBB2

0.787

PGR

ERBB3

0.502

RARA

FLT3

0.666

RET

NR4A2

0.628

RET

RARA

0.402

RET

DHTR

0.478

THRA

ROS1

0.539

TIE1

NR2E1

0.682

  1. * The interactions shown in bold are validated experimentally (see text for more details).
  2. ** Interaction score computed by STRING
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Biology Direct

ISSN: 1745-6150

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