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Table 1 NR- RTK interactions and their combined scores

From: Application of computational approaches to study signalling networks of nuclear and Tyrosine kinase receptors

node1 node2 Combined score**
ALK RARA 0.659
CSF1R NR3C1 0.700
CSF1R THRA 0.675
DHTR* ERBB2 0.786
DHTR EGFR 0.970
DHTR ERBB3 0.478
EGFR RARB 0.461
EGFR THRA 0.820
EGFR ESR1 0.971
EPHB4 NR3C1 0.467
EPHB6 ESR1 0.636
ERBB2 RARA 0.637
ERBB2 ESR1 0.971
ERBB2 THRA 0.810
ERBB2 NR1D1 0.441
ERBB3 ESR1 0.700
ERBB3 ESRRB 0.433
ERBB4 ESR1 0.550
ERBB4 PGR 0.588
ESR2 ERBB4 0.631
ESR2 ERBB2 0.777
ESR2 IGF1R 0.594
ESR2 ERBB3 0.689
ESR2 CSF1R 0.747
ESR2 MET 0.561
ESR2 EGFR 0.775
FGFR4 NR1H4 0.509
HNF4A INSR 0.797
IGF1R ESR1 0.920
NR2F2 PDGFRA 0.445
NR4A2 EPHB1 0.832
NTRK2 THRA 0.826
PDGFRB NR3C1 0.545
PGR EGFR 0.726
PGR ERBB2 0.787
PGR ERBB3 0.502
RARA FLT3 0.666
RET NR4A2 0.628
RET RARA 0.402
RET DHTR 0.478
THRA ROS1 0.539
TIE1 NR2E1 0.682
  1. * The interactions shown in bold are validated experimentally (see text for more details).
  2. ** Interaction score computed by STRING