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Table 1 The expected fates of recruited SCs under intense intercellular communication as depending on the recruited SC kinetic parameters

From: Disruption of a Quorum Sensing mechanism triggers tumorigenesis: a simple discrete model corroborated by experiments in mammary cancer stem cells

Class

Transition to maturation

Characteristic parameters

Formal condition

a

Dominant

large DC life span

Ψ ≤ Φ -Θ

b

depends on recruited SC number

intermediate DC life span

Φ - Θ < Ψ ≤ Φ + 1

c

none

DC life span shorter than differentiation time

Ψ > Φ + 1