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Table 1 Identification of representative Ago mid domain sequences

From: The human Ago2 MC region does not contain an eIF4E-like mRNA cap binding motif

Hit

GI

Round

E-value

Range

Initial Coverage

Final Coverage

Hs Piwi4

116242716

4

3.0E-05

515–605

0.67

0.90

Sp Ago

19075282

5

1.0E-05

446–558

0.83

0.99

At Zll

15239989

5

3.0E-04

566–682

0.86

0.99

Dm Ago2

24664664

5

4.0E-03

868–943

0.56

0.96

Dm Ago1

24653501

6

6.0E-22

587–698

0.82

0.93

Hs Ago2

29171734

6

4.0E-20

461–574

0.84

0.93

Ce Alg1

25148113

6

5.0E-20

596–717

0.90

0.96

Ce Ppw2

17510939

7

3.0E-06

552–665

0.84

0.96

  1. PSI-BLAST results reported for initial detection of representative hits using a sequence query corresponding to the mid domain structure. Coverage is calculated as the quotient of the range of either the initial hit or the hit after convergence and the range of query.