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Table 2 Over represented KEGG pathways using Illumina sequencing.

From: Transcript length bias in RNA-seq data confounds systems biology

Term

Count

Pop Hits

PValue

Benjamini

hsa04610:Complement and coagulation cascades

60

68

3.08E-08

7.11E-06

hsa04910:Insulin signaling pathway

96

133

1.06E-04

0.0122

hsa00020:Citrate cycle (TCA cycle)

25

27

2.23E-04

0.0170

hsa00120:Bile acid biosynthesis

31

36

4.23E-04

0.0242

hsa00071:Fatty acid metabolism

37

45

5.35E-04

0.0244

hsa00980:Metabolism of xenobiotics by cytochrome P450

50

65

7.29E-04

0.0277

hsa00190:Oxidative phosphorylation

85

121

0.001155

0.0374

hsa00310:Lysine degradation

38

48

0.001627

0.0459

hsa04510:Focal adhesion

128

196

0.004824

0.0966

hsa00051:Fructose and mannose metabolism

33

42

0.00463

0.102

hsa00650:Butanoate metabolism

35

45

0.00448

0.109

hsa04520:Adherens junction

52

74

0.0129

0.171

hsa04810:Regulation of actin cytoskeleton

133

208

0.0116

0.175

hsa04912:GnRH signaling pathway

64

93

0.0109

0.177

hsa00010:Glycolysis/Gluconeogenesis

43

59

0.0110

0.177

hsa00230:Purine metabolism

94

143

0.0128

0.180

hsa00280:Valine, leucine and isoleucine degradation

33

44

0.0147

0.183

hsa05010:Alzheimer's disease

23

29

0.0200

0.228

hsa00620:Pyruvate metabolism

31

42

0.0262

0.253

hsa05210:Colorectal cancer

57

84

0.0250

0.254

hsa00260:Glycine, serine and threonine metabolism

33

45

0.0241

0.256

hsa04514:Cell adhesion molecules (CAMs)

82

126

0.0285

0.262

hsa04670:Leukocyte transendothelial migration

74

113

0.0315

0.275

hsa00220:Urea cycle and metabolism of amino groups

23

30

0.0359

0.297

hsa04360:Axon guidance

81

126

0.0429

0.313

hsa04370:VEGF signaling pathway

47

69

0.0401

0.315

hsa05120:Epithelial cell signaling in Helicobacter pylori infection

47

69

0.0401

0.315

hsa00052:Galactose metabolism

24

32

0.0448

0.315

hsa00480:Glutathione metabolism

27

37

0.0495

0.315

hsa00903:Limonene and pinene degradation

22

29

0.0488

0.319

hsa05040:Huntington's disease

22

29

0.0488

0.319

hsa03320:PPAR signaling pathway

47

70

0.0549

0.327

hsa00380:Tryptophan metabolism

41

60

0.0535

0.328

hsa05211:Renal cell carcinoma

45

67

0.0605

0.330

hsa00591:Linoleic acid metabolism

23

31

0.0596

0.333

hsa01510:Neurodegenerative Diseases

28

39

0.0585

0.336

hsa00410:beta-Alanine metabolism

19

25

0.0717

0.356

hsa00363:Bisphenol A degradation

12

14

0.0691

0.360

hsa00640:Propanoate metabolism

24

33

0.0712

0.361

hsa00860:Porphyrin and chlorophyll metabolism

27

38

0.0752

0.363

hsa00740:Riboflavin metabolism

13

16

0.0932

0.424

sa00770:Pantothenate and CoA biosynthesis

13

16

0.0932

0.424

hsa04530:Tight junction

81

130

0.0991

0.429

  1. Categories in bold are not found to be over represented in the microarray data.
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